Hematopoietic Stem Cell Transplantation Impact on Patients' Perceived Quality of Life: A Longitudinal Study.

OBJECTIVE: The aim of this paper was to evaluate the quality of life of adult patients with onco-hematological disease treated with hematopoietic stem cell transplantation up to two years post-transplantation. METHOD: A quantitative, observational, longitudinal, and analytical study was conducted with 121 participants diagnosed with onco-hematological cancer who underwent hematopoietic stem cell transplantation between October 2017 and September 2019, with a 2-year post-transplantation follow-up, of whom only 39 completed the study. The Functional Assessment of Cancer Therapy-Bone Marrow Transplantation (FACT-BMT) questionnaire and its subscales, Functional Assessment of Cancer Therapy-General (FACT-BMT) and Functional Assessment of Cancer Therapy Trial Outcome Index (FACT-TOI), developed by the Functional Assessment of Chronic Illness Therapy (FACIT) and validated for Spain, were used to assess quality of life. RESULT: The average age for hematopoietic stem cell transplantation was 54 years, with a majority of male participants. The evaluation of quality of life showed a decrease at the time of hospital discharge, followed by a progressive improvement up to one year after the transplantation. There was a significant difference in the quality of life questionnaire scores between both sexes during all stages of the research, with higher scores in male participants. The length of hospital stay significantly affected patients' physical and functional well-being, and marital status was related to differences in the perception of quality of life. CONCLUSIONS: Despite the initial decrease in quality of life for patients undergoing hematopoietic stem cell transplantation, levels of quality of life similar to baseline are regained one year after the transplantation. Sociodemographic variables are related to how these patients perceive their quality of life. However, further studies with a larger sample size are needed for more precise results.

Paternal symptoms of anxiety and depression in the first month after childbirth: A comparison between fathers of full term and preterm infants.

BACKGROUND: Although men have a higher risk of developing a mental disorder during the perinatal period, few studies have focused on new fathers' mental health screening. This study compares anxiety and depression symptoms between fathers with newborn infants in the neonatal intensive care unit (NICU) and fathers of healthy full-term infants, assessing the impact of stress caused by the NICU.. METHODS: A longitudinal and prospective study with control (n= 33) and study groups (n=51) was designed. The dependent variables assessed were post-natal depression and anxiety-state while the social and demographic information, health background and the parental stress in the neonatal unit were the independent variables. The fathers were assessed twice during the first month after birth. RESULTS: Significant differences in the EPDS scores were found between both groups in the first assessment (p = .006) but not in the second assessment (p = .60). Significant differences in STAI scores were found between the groups for both assessments (p = .003 and p = .002). The stress caused by the infant's appearance and behavior was predictive of depression and anxiety in the study group. LIMITATIONS: The sample was collected at one hospital, immigrants were underrepresented, and no prenatal assessment of paternal mental health is available. CONCLUSIONS: Our results suggest that the hospitalization of newborn infants increases the risk of developing anxiety or depression disorder in fathers. Health providers should be aware of the emotional changes in men shortly after childbirth and include them in the screening of and support for mental health disorders.

Uso de pantallas de visualización de datos e hipertensión ocular en trabajadores de la Administración local / Use of data displai screens and ocular hypertension in local public sectorworkers

Objetivo: El objetivo principal de este estudio es conocer la relación entre la exposición al trabajo con pantallas de visualización de datos (PVD) y la hipertensión ocular (HTO).Métodos: Estudio transversal en población trabajadora en la Administración local (Diputación Provincial de Valencia).Se recogieron datos de 620 personas a lo largo de 25 meses, en una Unidad de Salud Laboral, aprovechando los registros efectuados durante el examen de salud periódico. La presión intraocular (PIO) se obtuvo con un tonómetro de rebote portátil y validado para screening, estableciéndose el punto de corte para HTO en 22 mmHg. Como covariables se tuvieron en cuenta características biológicas y otras relacionadas con el trabajo. Se efectuó estadística descriptiva de los datos, pruebas no paramétricas con nivel de significación del 95% y regresión logística con p<0,1 como nivel de significación de la prueba de verosimilitud. Resultados: La media de edad de la población estudiada es de 52,8 años. La prevalencia de HTO es del 3,5% (el 5,1%en los hombres y el 1,2%en las mujeres; p=0,012). No se han encontrado diferencias significativas en HTO en cuanto a horas diarias de exposición a PVD (p=0,395). La regresión logística corrobora la relación entre HTO y el sexo, afectando menos a las mujeres (OR = 0,234; IC95%: 0,068-0,799; p=0,020).Conclusiones: No se ha encontrado relación entre la hipertensión ocular y el tiempo de exposición a pantallas de visualización de datos (PVDs). La regresión logística apunta hacia cierta relación entre la hipertensión ocular y el sexo, con mayor predisposición hacia los hombres

Objective: The main objective of this study is to examine the association between work with data display screens (DDS) and ocular hypertension (OHT). Methods: A cross-sectional study among local public sector workers (Diputación Provincial de Valencia). Data from 620 people were collected over 25 months, from periodic medical examinations performed at an occupational health unit. Intraocular pressure (IOP) was obtained with a portable puff tonometer validated for screening, establishing the cut-off point for OHT at 22 mmHg. Both biological characteristics and other work-related variables were taken into account as covariates. Descriptive statistics of the data were obtained, together with nonparametric tests with a level of significance of 95% and logistic regression with p<0.1 as the level of significance of the likelihood test. Results: The average age of the study population is 52.8 years. The prevalence of OHT was 3.5% (5.1% among men and 1.2% among women; p = 0.012). No significant associations were found between hours of DDS-related work and OHT were found (p = 0.395). Logistic regression corroborated the association between gender and OHT, with women less affected (OR = 0.234; 95%CI: 0.068-0.799; p=0.020). Conclusions: In our study, no associations were found between time of exposure to data display screens and ocular hypertension. Logistic regression points to a certain association between ocular hypertension and gender, with men being more predisposed

[Use of data display screens and ocular hypertension in local public sector workers]. / Uso de pantallas de visualización de datos e hipertensión ocular en trabajadores de la Administración local.

OBJECTIVE: The main objective of this study is to examine the association between work with data display screens (DDS) and ocular hypertension (OHT). METHODS: A cross-sectional study among local public sector workers (Diputación Provincial de Valencia). Data from 620 people were collected over 25 months, from periodic medical examinations performed at an occupational health unit. Intraocular pressure (IOP) was obtained with a portable puff tonometer validated for screening, establishing the cut-off point for OHT at 22 mmHg. Both biological characteristics and other work-related variables were taken into account as covariates. Descriptive statistics of the data were obtained, together with nonparametric tests with a level of significance of 95% and logistic regression with p 〈0.1 as the level of significance of the likelihood test. RESULTS: The average age of the study population is 52.8 years. The prevalence of OHT was 3.5% (5.1% among men and 1.2% among women; p=0.012). No significant associations were found between hours of DDS-related work and OHT were found (p=0.395). Logistic regression corroborated the association between gender and OHT, with women less affected (OR = 0.234; 95%CI: 0.068 - 0.799; p=0.020). CONCLUSIONS: In our study, no associations were found between time of exposure to data display screens and ocular hypertension. Logistic regression points to a certain association between ocular hypertension and gender, with men being more predisposed.

OBJETIVO: El objetivo principal de este estudio es conocer la relación entre la exposición al trabajo con pantallas de visualización de datos (PVD) y la hipertensión ocular (HTO). MÉTODOS: Estudio transversal en población trabajadora en la Administración local (Diputación Provincial de Valencia). Se recogieron datos de 620 personas a lo largo de 25 meses, en una Unidad de Salud Laboral, aprovechando los registros efectuados durante el examen de salud periódico. La presión intraocular (PIO) se obtuvo con un tonómetro de rebote portátil y validado para screening, estableciéndose el punto de corte para HTO en 22 mmHg. Como covariables se tuvieron en cuenta características biológicas y otras relacionadas con el trabajo. Se efectuó estadística descriptiva de los datos, pruebas no paramétricas con nivel de significación del 95% y regresión logística con p 〈0,1 como nivel de significación de la prueba de verosimilitud. RESULTADOS: La media de edad de la población estudiada es de 52,8 años. La prevalencia de HTO es del 3,5% (el 5,1% en los hombres y el 1,2%en las mujeres; p=0,012). No se han encontrado diferencias significativas en HTO en cuanto a horas diarias de exposición a PVD (p=0,395). La regresión logística corrobora la relación entre HTO y el sexo, afectando menos a las mujeres (OR = 0,234; IC95%: 0,068 − 0,799; p=0,020). CONCLUSIONES: No se ha encontrado relación entre la hipertensión ocular y el tiempo de exposición a pantallas de visualización de datos (PVDs). La regresión logística apunta hacia cierta relación entre la hipertensión ocular y el sexo, con mayor predisposición hacia los hombres.